Fatigue also plays a factor when cold-weather teams play in hot weather during the early months of the season. A new fatigue system was implemented, disallowing users from taking a scrambling quarterback and repeatedly running around behind the line of scrimmage for very long gains. Another updated feature - dubbed Hit Stick 2.0 - allows players to hit high or low by flicking the analog stick up or down. Madden 08 brings back some features for its online play for example, there is the return of Season Mode and tournaments held online. Features of the new animation system include mid-air collisions, big-time, one-handed catches, hurdles, sideline catches and gang tackling. Players are no longer locked into animations but are now controlled more by the player. A new branching animation system allows dynamic gameplay for the first time in the franchise. Madden 08 runs at 60 frames per second on the Xbox 360, and 30 frames per second on the PlayStation 3. It is also the last game in the series to include all 6 NFL Europa teams, as the league folded after its 2007 season. Madden NFL 08 has sold 4.5 million copies.

By December 31, 2015, the Xbox 360 version had sold 1,169,587 copies in the United States. A Spanish-language version of the game was released on Decemfor the PlayStation 2 and Xbox 360 platforms, featuring ESPN Deportes announcer Álvaro Martín. After the August 14 release date came and went without a Mac release, however, EA said it would be delayed until September or October 2007. had announced in June 2007 that a version for Mac OS X would be released at the same time as the other versions.

This was the last version of Madden to be released for Microsoft Windows until Madden NFL 19, and the last video game for the GameCube produced and released in North America. There was also a version for Mac released on September 1, 2007. This was the first Madden game made for 11 different platforms, it was released on August 14, 2007, for Xbox 360, Wii, PlayStation 3, PlayStation 2, Nintendo DS, PlayStation Portable, Xbox, GameCube and Microsoft Windows. It features Tennessee Titans quarterback Vince Young on the cover San Diego Chargers defensive end Luis Castillo was the cover athlete for the Spanish-language version. It is the 19th installment in the Madden NFL video game franchise.

Madden NFL 08 is a 2007 American football video game based on the National Football League that was published by EA Sports and developed by EA Tiburon.

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